LeXso RP Panel v1.0
- #LX11431
The LeXso RP Panel v1.0 is an advanced targeted enrichment solution specifically engineered for the high-throughput detection and precise identification of hundreds of respiratory pathogens. By targeting characteristic genomic regions across a vast spectrum of microorganisms—including RNA viruses, DNA viruses, bacteria, fungi, mycoplasma, and chlamydia—this panel provides a panoramic view of respiratory infections.
Precision Surveillance and Diagnostic Support
Designed for use with the LeXso Hybrid Capture System, the RP Panel covers over 99% of common respiratory pathogens. It is an essential tool for laboratories focused on:
- Multiplex Pathogen Co-detection: Identifying complex co-infections in a single assay.
- Precise Typing: Resolving 232 different subtypes for accurate clinical and epidemiological assessment.
- Epidemiological Management: Enhancing the monitoring and tracking of community-wide infection trends.
- Product Details
- Kit Content
- FAQ
- Ordering Information
- Resources
Advanced Multiplex Pathogen Detection
- Simultaneously detect a wide array of pathogens including bacteria, viruses (both DNA and RNA), fungi, mycoplasma, and chlamydia within a single, streamlined workflow.
High-Resolution Identification and Typing
- Enables the precise identification of 232 subtypes, including critical respiratory groups such as Adenovirus, Rhinovirus, Parainfluenza virus, and Enterovirus.
In-depth Influenza A Virus Variant Tracking
- Features specialized probes targeting the complete coding sequences of the major 16 HA subtypes and 9 NA subtypes, providing superior resolution for strain evolution and variant monitoring.
Rapid Turnaround & Efficiency
- When paired with the LeXPrep DualPrep Module, the panel allows for the synchronous preparation of RNA and DNA libraries, moving from sample to comprehensive results in a single day.
Exceptional Sensitivity
- Optimized probe kinetics ensure the detection of low-abundance pathogens, facilitating early diagnosis even in samples with high background genomic noise.
| Virus (34 species) | DNA virus (11 species 29 subtypes) | Human Polyomavirus 1 (BK Polyomavirus), Human Polyomavirus 2 (JC Polyomavirus), Human Polyomavirus 4 (WU Polyomavirus), Human Mastadenovirus B (3 /7/11/14/16/21/34/35/50/55 subtype), Human Mastadenovirus C (1/2/5/6/57 subtype), α Herpesvirus (1/2/3 subtype), γ Herpesvirus (4 subtype), β Herpesvirus (5/6/7 subtype), Human Bocavirus (1/2/3/4 subtype), Human Parvovirus B19, Monkeypox Virus |
| RNA virus (23 species 203 subtypes) | Human Rhinovirus A (77 subtypes: 1-2, 7-13, 15-16, 18-25, 28-34, 36, 38-41, 43, 45-47, 49-51, 53-68, 71, 73-78, 80-82, 85, 88-90, 94-96, 98, 100-101, 103, 105-106), Human Rhinovirus B (25 subtypes: 3-6, 14, 17, 26, 27, 35, 37, 42, 48, 52, 69, 70, 72, 79, 83-84, 86, 91-93, 97, 99), Human Rhinovirus C (32 subtypes: 1-3, 5-9, 11-13, 15, 17-19, 22-24, 26, 30-33, 35, 40-44, 47, 53, 55), Human Respiratory Syncytial Virus (A/B subtype), Human Parainfluenza Virus (1/3 subtype), Human Parainfluenza Virus (2/4 subtype), Mumps Virus, Influenza A Virus (coding gene), Influenza B Virus, Coxsackievirus (24 subtypes: A1-A3, A5-A8, A10, A12-A22, B1, B3-B6), Echovirus (11 subtypes: E1, E3-E7, E9, E11, E25, E30, E32), Enterovirus (25 subtypes: E1, E3-7, E11, E25, E30, E32, A71, A90, A92, A120, A123, B69, C99, C105, C109, C113, C116, D68, D94, D111, J103), Human Metapneumovirus, Measles Virus (Genotype D8), Rubella Virus (Genotype 2B), SARS-CoV, SARS-CoV-2, MERS, Human Coronavirus (OC43, HKU1), Human Coronavirus (229E, NL63) | |
| Bacteria (57 species) | Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Streptococcus pneumoniae, streptococcus dysgalactiae, Streptococcus intermadius, Streptococcus anginosus, Streptococcus constellatus, Streptococcus pyogenes, Streptococcus agalactiae, Peptostreptococcus anaerobius, Mycobacterium tuberculosis , Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium lepromatosis, Mycobacterium asiaticum, Mycobacterium szulgai, Mycobacterium ulcerans, Mycobacterium xenopi, Mycobacterium scrofulaceum, Mycobacterium simiae, Mycobacterium novum, Mycobacterium haemophilum, Mycobacterium botniense, Mycobacterium kansasii, Mycobacterium abscessus, Mycobacterium chelonae, Neisseria gonorrhoeae , Neisseria meningitidis , Bacillus anthracis , Bacillus cereus, Arcanobacterium haemolyticum, Corynebacterium diphtheriae , Fusobacterium necrophorum, Haemophilus influenzae, Haemophilus parainfluenzae, Nocardia abscessus, Nocardia asteroides, Nocardia brasiliensis, Serratia marcescens, Moraxella catarrhalis, Bordetella pertussis, Bordetella parapertussis, Bordetella bronchiseptica, Bordetella holmesii, Legionella pneumophila, Elizabethkingia meningoseptica, Coxiella burnetii, Brucella abortus, Brucella anthropi, Brucella melitensis | |
| Fungi (13 species) | Pneumocystis jirovecii, Cryptococcus neoformans, Cryptococcus gattii, Trichosporon*, Mucor*, Candida albicans, Candida tropicalis, Candida dubliniensis, Candida parapsilosis, Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Aspergillus nidulans, Histoplasma capsulatum | |
| Others (4 species) | Mycoplasmoides pneumoniae, Chlamydia pneumoniae, Chlamydia psittaci, Chlamydia trachomatis | |
*Species not identified.
| Catalog | Color Of Tube Cap | Component | Volume | Package/Storage |
| LX11431 | ● | LeXso RP Panel v1.0, 96 rxn | 210 μL | -20℃ |
Yes. When used in conjunction with the LeXPrep RNA & DNA Library DualPrep Module, the system performs a single process for RNA and DNA co-preparation. This allows for the synchronous capture and sequencing of both viral types (e.g., Influenza and Adenovirus) from a single mixed pathogenic sample.
The LeXso RP Panel utilizes an exhaustive probe design that covers the entire coding regions of 16 HA and 9 NA subtypes. This “whole-gene” approach ensures that even if a virus undergoes significant antigenic drift or shift, the system maintains high capture efficiency and provides enough data for precise variant tracking.
Absolutely. The LeXso RP workflow is fully optimized for the LeXBot automation series. Automation significantly reduces manual handling time and the risk of cross-contamination, which is particularly critical when dealing with high-sensitivity pathogen detection.
While standard mNGS provides a broad view, it often suffers from low sensitivity for rare pathogens due to high host-DNA background. The LeXso RP Panel specifically enriches pathogen sequences, increasing the effective sequencing depth by orders of magnitude and allowing for lower-cost, high-sensitivity detection.
| Product | Catalog |
|---|---|
| LeXso RP Panel v1.0, 96 rxn | LX11431 |
For inquiries or to request a formal quotation, please contact us at support@lexigenbio.com