The LeXPrep rRNA Blocking Reagent is a specialized solution engineered for high-throughput sequencing platforms, designed to rapidly and effectively deplete ribosomal RNA (rRNA) from total RNA samples. By streamlining the removal of unwanted transcripts, this module enhances sequencing depth for target sequences and improves overall data quality.


We provide personalized, professional advice for researchers requiring custom-designed probes for unique species. To discuss your project or request a quotation, please send your request to our technical team at support@lexigenbio.com
For research use only. Not for use in diagnostic procedures.
| Catalog | Color Of Tube Cap | Product | Volume | Package/Storage |
| LX02901 | ● | LeXPrep rRNA Blocking Reagent (H), 24 rxn | 30 μL | −20°C |
| LX02902 | ● | LeXPrep rRNA Blocking Reagent (H), 96 rxn | 115μL | −20°C |
| LX02911 | ● | LeXPrep rRNA Blocking Reagent (Zebrafish), 24 rxn | 30 μL | −20°C |
| LX02912 | ● | LeXPrep rRNA Blocking Reagent (Zebrafish), 96 rxn | 115μL | −20°C |
| LX02921 | ● | LeXPrep rRNA Blocking Reagent (HMR), 24 rxn | 30 μL | −20°C |
| LX02922 | ● | LeXPrep rRNA Blocking Reagent (HMR), 96 rxn | 115μL | −20°C |
| LX02931 | ● | LeXPrep rRNA Blocking Reagent (Plant), 24 rxn | 30 μL | −20°C |
| LX02932 | ● | LeXPrep rRNA Blocking Reagent (Plant), 96 rxn | 115μL | −20°C |
| LX02951 | ● | LeXPrep rRNA Blocking Reagent (Bacteria), 24 rxn | 30 μL | −20°C |
| LX02952 | ● | LeXPrep rRNA Blocking Reagent (Bacteria), 96 rxn | 115μL | −20°C |
| LX02941 | ● | LeXPrep Globin mRNA Blocking Reagent, 24 rxn | 30 μL | −20°C |
| LX02942 | ● | LeXPrep Globin mRNA Blocking Reagent, 96 rxn | 115μL | −20°C |
| LX029XX | ● | LeXPrep rRNA Blocking Reagent (Custom), 96 rxn | 115μL | −20°C |
A: This solution is compatible with RNA samples from a wide range of cell and tissue sources across varying degradation levels. However, it is not recommended for severely degraded FFPE samples where the DV200 is less than 20%.
A: Yes. This solution can be seamlessly integrated into various RNA-Seq library preparation workflows. If opting for a third-party kit, we specifically recommend the NEBNext® Ultra™ II RNA Library Prep Kit for Illumina® (NEB, Cat # E7770L) or the KAPA RNA HyperPrep Kit (Roche, Cat # KK8541). For inquiries regarding other brands, please consult the technical support team at support@lexigenbio.com
A: This solution utilizes a high concentration of rRNA ssDNA blocking reagents. When used alongside the LeXPrep Total RNA-To-DNA Module, trace amounts of residual ssDNA may remain in the purified dsDNA product. Because nucleic acid fluorescence quantifiers (like Qubit) can be influenced by residual ssDNA, the reported yield may appear slightly elevated. However, this does not interfere with downstream applications. We recommend adjusting adapter dilution factors and PCR cycles based on your specific RNA source and input amount.
| Product | Catalog |
|---|---|
| LeXPrep rRNA Blocking Reagent (Human), 24 rxn | LX02901 |
| LeXPrep rRNA Blocking Reagent (Human), 96 rxn | LX02902 |
| LeXPrep rRNA Blocking Reagent (Zebrafish), 24 rxn | LX02911 |
| LeXPrep rRNA Blocking Reagent (Zebrafish), 96 rxn | LX02912 |
| LeXPrep rRNA Blocking Reagent (HMR), 24 rxn | LX02921 |
| LeXPrep rRNA Blocking Reagent (HMR), 96 rxn | LX02922 |
| LeXPrep rRNA Blocking Reagent (Plant), 24 rxn | LX02931 |
| LeXPrep rRNA Blocking Reagent (Plant), 96 rxn | LX02932 |
| LeXPrep rRNA Blocking Reagent (Bacteria), 24 rxn | LX02951 |
| LeXPrep rRNA Blocking Reagent (Bacteria), 96 rxn | LX02952 |
| LeXPrep Globin mRNA Blocking Reagent, 24 rxn | LX02941 |
| LeXPrep Globin mRNA Blocking Reagent, 96 rxn | LX02942 |
| LeXPrep rRNA Blocking Reagent (Custom), 96 rxn | LX029XX |
For inquiries or to request a formal quotation, please contact us at support@lexigenbio.com